Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6059352 | 0.87 | LCK (0.40) | PI4KBLCKPTGDR2SCN9A | |
| SCHEMBL3888187 | 0.76 | LCK (0.39) | PI4KBLCKPTGDR2SCN9A | |
| SCHEMBL6059214 | 0.76 | LCK (0.39) | PI4KBLCKPTGDR2SCN9A | |
| SCHEMBL6059133 | 0.73 | ALDH1A1 (0.36) | LCKSCN9A | |
| SCHEMBL29112758 | 0.72 | CNR2 (0.41) | CNR2LCKSCN9A | |
| SCHEMBL6999990 | 0.72 | MAPKAPK2 (0.38) | LCKSCN9A | |
| SCHEMBL6469040 | 0.71 | LCK (0.46) | LCKSCN9A | |
| SCHEMBL6059110 | 0.71 | BACE1 (0.37) | LCKPTGDR2SCN9A | |
| SCHEMBL6059293 | 0.71 | LCK (0.34) | PI4KBLCKPTGDR2SCN9A | |
| SCHEMBL6059061 | 0.71 | PPARG (0.37) | LCKPTGDR2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1180098-A1 | NEW COMPOUNDS | AstraZeneca AB (SE) | 2002-02-20 | — | — | EP | disclosed |
| WO-2000066557-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 2000-11-09 | — | — | WO | disclosed |