Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 6/20 | 0.45 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 5/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31107757 | 0.85 | ACE (0.49) | ITGB3ITGA2BCTSKPPARAPPARG | |
| SCHEMBL4644244 | 0.80 | P2RY2 (0.47) | ALDH1A1TSHRITGB3ITGA2BCTSK | |
| SCHEMBL14150791 | 0.78 | CTSK (0.56) | ALDH1A1TSHRITGB3ITGA2BCTSK | |
| SCHEMBL6837916 | 0.78 | CTSK (0.56) | ALDH1A1TSHRITGB3ITGA2BCTSK | |
| SCHEMBL6745774 | 0.78 | CTSK (0.56) | ALDH1A1TSHRITGB3ITGA2BCTSK | |
| SCHEMBL14598338 | 0.78 | CTSS (0.62) | CTSKCTSSPTPN1 | |
| SCHEMBL15124943 | 0.78 | MEN1 (0.51) | ALDH1A1TSHRITGB3ITGA2BCTSK | |
| SCHEMBL13669688 | 0.77 | MEN1 (0.54) | ALDH1A1TSHRITGB3ITGA2BCTSK | |
| SCHEMBL12238298 | 0.77 | MEN1 (0.71) | ALDH1A1TSHRITGB3ITGA2BCTSK | |
| SCHEMBL903957 | 0.77 | MEN1 (0.71) | ALDH1A1TSHRITGB3ITGA2BCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019386-A1 | REVERSE HYDROXAMATE DERIVATIVES AS METALLOPROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998038179-A1 | REVERSE HYDROXAMATE DERIVATIVES AS METALLOPROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1998-09-03 | — | — | WO | disclosed |