Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 8/20 | 0.47 |
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 4/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10129663 | 0.85 | PPARA (0.44) | ACEPPARAPPARGPPARDAPP | |
| SCHEMBL7417672 | 0.85 | ALDH1A1 (0.48) | ACEPPARAPPARGPPARDIDO1 | |
| SCHEMBL644995 | 0.82 | PPARA (0.44) | ACEPPARAPPARGPPARDAPP | |
| SCHEMBL29039971 | 0.81 | ACE (0.54) | ACEPPARAPPARGPPARDAPP | |
| SCHEMBL28583142 | 0.81 | ACE (0.54) | ACEPPARAPPARGPPARDAPP | |
| SCHEMBL4597846 | 0.81 | CTSK (0.47) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL646896 | 0.78 | KMT2A (0.49) | ACEPPARAPPARGPPARD | |
| SCHEMBL215178 | 0.76 | ACE (0.56) | ACEPPARAPPARGPPARDIDO1 | |
| SCHEMBL215179 | 0.76 | ACE (0.56) | ACEPPARAPPARGPPARDIDO1 | |
| SCHEMBL268002 | 0.76 | ACE (0.56) | ACEPPARAPPARGPPARDIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235389-A1 | P53 MODULATORS | NESTED THERAPEUTICS, INC. (US) | 2025-11-13 | — | — | WO | disclosed |
| WO-2024215802-A1 | BENZOFURANYL AND BENZOTHIENYL COMPOUNDS AS P53 MODULATORS | NESTED THERAPEUTICS, INC. (US) | 2024-10-17 | — | — | WO | disclosed |