Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 8/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | MGAM | O43451 | 3/20 | 0.37 |
| ▸ | SI | P14410 | 3/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5620810 | 0.82 | PARP1 (0.64) | PARP1PARP2 | |
| SCHEMBL7759238 | 0.82 | MGAM (0.51) | AURKAACHEPARP1PARP2GAA | |
| SCHEMBL11198421 | 0.80 | HRH4 (0.58) | NPY5RAURKAPARP1HRH4ALKBH3 | |
| SCHEMBL6864586 | 0.79 | PARP1 (0.45) | NPY5RPARP1PARP2 | |
| SCHEMBL7411395 | 0.77 | NPY5R (0.45) | NPY5RAURKABCHEACHEPARP1 | |
| SCHEMBL7600366 | 0.77 | HTR3A (0.59) | NPY5RAURKABCHEACHEPARP1 | |
| SCHEMBL7762915 | 0.76 | MGAM (0.55) | AURKAACHEPARP1PARP2GAA | |
| SCHEMBL5620966 | 0.76 | PARP1 (0.69) | PARP1PARP2 | |
| SCHEMBL7417491 | 0.74 | NPY5R (0.45) | NPY5RPARP1PARP2 | |
| SCHEMBL6869126 | 0.73 | PARP1 (0.48) | NPY5RPARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001082877-A2 | USE OF PARP INHIBITORS IN COSMETIC PREPARATIONS | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-08 | — | — | WO | disclosed |
| EP-1133477-A1 | SUBSTITUTED BENZIMIDAZOLES AND THEIR USE AS PARP INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000032579-A1 | SUBSTITUTED BENZIMIDAZOLES AND THEIR USE AS PARP INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-08 | — | — | WO | disclosed |