Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | CCR3 | P51677 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412259 | 0.90 | MCHR1 (0.71) | MCHR1HTR2ACCR3 | |
| SCHEMBL7412406 | 0.88 | MEN1 (0.66) | MCHR1KMT2ACCR3 | |
| SCHEMBL7304448 | 0.88 | MCHR1 (0.65) | MCHR1SIGMAR1ACHEKMT2ACCR3 | |
| SCHEMBL7414680 | 0.87 | DRD4 (0.66) | MCHR1SIGMAR1ACHEHTR2A | |
| SCHEMBL7415439 | 0.86 | MCHR1 (0.72) | MCHR1SIGMAR1ACHEHTR2ACCR3 | |
| SCHEMBL6344464 | 0.84 | HTR2A (0.73) | ACHEKMT2AHTR2A | |
| SCHEMBL4795273 | 0.83 | S1PR5 (0.62) | MCHR1SIGMAR1ACHEKMT2ACCR3 | |
| SCHEMBL4795270 | 0.83 | S1PR5 (0.62) | MCHR1SIGMAR1ACHEKMT2ACCR3 | |
| SCHEMBL6529983 | 0.81 | CCR8 (0.70) | HTR2ACCR3 | |
| SCHEMBL9171573 | 0.81 | SIGMAR1 (0.70) | MCHR1SIGMAR1ACHEKMT2ACCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198449-A | N-substituted alpha-arylazacycloalkylmethanamines and their use as cardiovascular agents | A. H. ROBINS COMPANY INCORPORATED (US) | 1993-03-30 | — | — | US | disclosed |