Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PDE9A | O76083 | 2/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419501 | 0.71 | AGTR1 (0.42) | ALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL6279539 | 0.70 | UCHL1 (0.46) | ALDH1A1HPGDAKT1CA1CA2 | |
| SCHEMBL7417812 | 0.70 | AGTR1 (0.52) | — | |
| SCHEMBL19845815 | 0.70 | CA2 (0.52) | KDM4EALDH1A1ALOX15AKT1CA1 | |
| SCHEMBL1979106 | 0.69 | CYP2A6 (0.48) | MAPTRAB9ACA1CA2CA9 | |
| SCHEMBL8872917 | 0.69 | ESR2 (0.51) | AKT1 | |
| SCHEMBL4662063 | 0.68 | CA2 (0.50) | KDM4EALDH1A1HPGDALOX15MAPT | |
| SCHEMBL4952656 | 0.68 | CA2 (0.58) | KDM4EALDH1A1HPGDALOX15AKT1 | |
| SCHEMBL14125769 | 0.67 | CA2 (0.61) | ALDH1A1HPGDAKT1RAB9ACA1 | |
| SCHEMBL9042997 | 0.67 | KDM4E (0.37) | KDM4EALDH1A1HPGDHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016071-A1 | HETEROCYCLIC DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-19 | — | — | WO | disclosed |