Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864847 | 0.95 | DUT (0.36) | DUTTSHR | |
| SCHEMBL8865215 | 0.93 | DUT (0.35) | DUT | |
| SCHEMBL6545080 | 0.86 | TSHR (0.42) | TSHR | |
| SCHEMBL11635954 | 0.85 | TSHR (0.50) | DUTTSHR | |
| SCHEMBL31651588 | 0.82 | CYP1A2 (0.47) | DUTTSHR | |
| SCHEMBL6545278 | 0.82 | TSHR (0.38) | TSHR | |
| SCHEMBL28516260 | 0.81 | DUT (0.39) | DUT | |
| SCHEMBL4590603 | 0.81 | ALDH1A1 (0.41) | DUTTSHR | |
| SCHEMBL875754 | 0.81 | DUT (0.39) | DUT | |
| SCHEMBL27321456 | 0.81 | DGKA (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733882-A | Retroviral protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-31 | — | — | US | disclosed |
| EP-0602069-A4 | RETROVIRAL PROTEASE INHIBITORS. | SMITHKLINE BEECHAM CORP (US) | 1995-05-03 | — | — | EP | disclosed |
| EP-0602069-A1 | RETROVIRAL PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-06-22 | — | — | EP | disclosed |
| WO-1993002057-A1 | RETROVIRAL PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-04 | — | — | WO | disclosed |