Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 4/20 | 0.42 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423601 | 0.88 | F2 (0.53) | MAPTTP53LMNAKMT2AALDH1A1 | |
| SCHEMBL7418302 | 0.88 | F2 (0.53) | MAPTTP53LMNAKMT2AALDH1A1 | |
| SCHEMBL7443425 | 0.87 | F2 (0.54) | CTSCKMT2ANPC1F2F10 | |
| SCHEMBL7359256 | 0.87 | F2 (0.53) | F2F10KLK1CTRC | |
| SCHEMBL7360493 | 0.87 | F2 (0.53) | F2F10KLK1CTRC | |
| Bromide SCHEMBL7365314 | 0.86 | F2 (0.52) | F2F10KLK1CTRC | |
| SCHEMBL7479296 | 0.86 | F2 (0.48) | TP53THRBF2F10KLK1 | |
| SCHEMBL7422682 | 0.86 | F2 (0.53) | F2F10KLK1CTRC | |
| Bromide SCHEMBL7365316 | 0.86 | F2 (0.52) | F2F10KLK1CTRC | |
| Hydrochloric Acid SCHEMBL7422561 | 0.82 | NPC1 (0.52) | MAPTLMNACTSCALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815103-A1 | TRYPSIN AND THROMBIN INHIBITORS | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029327-A1 | TRYPSIN AND THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |