Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.53 |
| ▸ | CTRC | Q99895 | 3/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | KLK1 | P06870 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443425 | 0.91 | F2 (0.54) | F2CTRCF10KLK1 | |
| SCHEMBL7359256 | 0.91 | F2 (0.53) | F2CTRCF10KLK1 | |
| SCHEMBL7360493 | 0.91 | F2 (0.53) | F2CTRCF10KLK1 | |
| Bromide SCHEMBL7365314 | 0.90 | F2 (0.52) | F2CTRCF10KLK1 | |
| SCHEMBL7479296 | 0.90 | F2 (0.48) | F2CTRCF10KLK1OPRK1 | |
| Bromide SCHEMBL7365316 | 0.90 | F2 (0.52) | F2CTRCF10KLK1 | |
| SCHEMBL7418302 | 0.88 | F2 (0.53) | F2CTRCF10KLK1OPRK1 | |
| SCHEMBL7423601 | 0.88 | F2 (0.53) | F2CTRCF10KLK1OPRK1 | |
| SCHEMBL7418322 | 0.86 | MAPT (0.44) | F2CTRCF10KLK1 | |
| Hydrochloric Acid SCHEMBL7422561 | 0.78 | NPC1 (0.52) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815103-A1 | TRYPSIN AND THROMBIN INHIBITORS | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029327-A1 | TRYPSIN AND THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |