Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.53 |
| ▸ | CTRC | Q99895 | 3/20 | 0.53 |
| ▸ | F10 | P00742 | 2/20 | 0.53 |
| ▸ | KLK1 | P06870 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418302 | 1.00 | F2 (0.53) | F2CTRCF10KLK1TP53 | |
| SCHEMBL7479296 | 0.92 | F2 (0.48) | F2CTRCF10KLK1TP53 | |
| SCHEMBL7359256 | 0.88 | F2 (0.53) | F2CTRCF10KLK1 | |
| SCHEMBL7360493 | 0.88 | F2 (0.53) | F2CTRCF10KLK1 | |
| SCHEMBL7443425 | 0.88 | F2 (0.54) | F2CTRCF10KLK1KMT2A | |
| SCHEMBL7418322 | 0.88 | MAPT (0.44) | F2CTRCF10KLK1TP53 | |
| Bromide SCHEMBL7365316 | 0.88 | F2 (0.52) | F2CTRCF10KLK1 | |
| SCHEMBL7422682 | 0.88 | F2 (0.53) | F2CTRCF10KLK1OPRK1 | |
| Bromide SCHEMBL7365314 | 0.88 | F2 (0.52) | F2CTRCF10KLK1 | |
| Hydrochloric Acid SCHEMBL7422561 | 0.84 | NPC1 (0.52) | F2MAPTLMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815103-A1 | TRYPSIN AND THROMBIN INHIBITORS | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029327-A1 | TRYPSIN AND THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |