Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472659 | 1.00 | MEN1 (0.31) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7380889 | 0.91 | MEN1 (0.32) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7380103 | 0.91 | MEN1 (0.32) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7410645 | 0.91 | MEN1 (0.32) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7386458 | 0.84 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL7382361 | 0.84 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL7383410 | 0.83 | CTSK (0.33) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7417510 | 0.83 | CTSK (0.33) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7385867 | 0.83 | CTSK (0.33) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7467337 | 0.80 | MEN1 (0.31) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019386-A1 | REVERSE HYDROXAMATE DERIVATIVES AS METALLOPROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998038179-A1 | REVERSE HYDROXAMATE DERIVATIVES AS METALLOPROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1998-09-03 | — | — | WO | disclosed |