Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.58 |
| ▸ | F2 | P00734 | 4/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | PLAT | P00750 | 1/20 | 0.45 |
| ▸ | PROC | P04070 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623712 | 0.89 | F10 (0.45) | F10F2PRSS1PLATPROC | |
| SCHEMBL8623715 | 0.85 | F10 (0.41) | F10F2PLATPROCPLG | |
| SCHEMBL2330834 | 0.84 | F10 (0.73) | F10F2PRSS1PLATPROC | |
| SCHEMBL2329937 | 0.78 | F10 (0.51) | F10F2PRSS1PLATPROC | |
| SCHEMBL8625062 | 0.77 | F10 (0.59) | F10F2PRSS1PLATPROC | |
| SCHEMBL8626509 | 0.76 | F10 (0.47) | F10F2PRSS1PLATPROC | |
| SCHEMBL2325595 | 0.76 | F10 (0.53) | F10F2PRSS1PLATPROC | |
| SCHEMBL2329162 | 0.74 | F10 (0.57) | F10F2PROCPLG | |
| SCHEMBL2329362 | 0.73 | F10 (0.71) | F10F2PRSS1PLATPROC | |
| SCHEMBL8623271 | 0.73 | F10 (0.60) | F10F2PROCPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894088-A4 | SUBSTITUTED SULFONIC ACID N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS | RHONE POULENC RORER PHARMA (US) | 2001-12-05 | — | — | EP | disclosed |
| EP-0894088-A1 | SUBSTITUTED SULFONIC ACID N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-02-03 | — | — | EP | disclosed |
| WO-1998024784-A1 | SUBSTITUTED SULFONIC ACID N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-06-11 | — | — | WO | disclosed |