Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15184555 | 0.81 | UHRF1 (0.39) | UHRF1 | |
| SCHEMBL4736010 | 0.72 | — | — | |
| SCHEMBL13180943 | 0.68 | — | — | |
| SCHEMBL7418341 | 0.67 | HTT (0.37) | — | |
| SCHEMBL21317734 | 0.65 | HTT (0.45) | UHRF1 | |
| SCHEMBL27955980 | 0.64 | UHRF1 (0.34) | UHRF1 | |
| SCHEMBL7410605 | 0.61 | AOC1 (0.42) | UHRF1 | |
| SCHEMBL28171461 | 0.60 | UHRF1 (0.31) | UHRF1 | |
| SCHEMBL25225301 | 0.60 | CCR4 (0.32) | — | |
| SCHEMBL30497655 | 0.60 | CCR4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002944-A | Compounds having cardiotonic activity | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0333727-A1 | HETEROCYCLIC SUBSTITUTED BICYCLOUREAS HAVING CARDIOTONIC ACTIVITY | RORER INTERNATIONAL (OVERSEAS) INC. (a Delaware corporation) (US) | 1989-09-27 | — | — | EP | disclosed |
| US-4859672-A | Pyrido[2,3-d]pyrimidinone and imidazo[4,5-b]pyrimidinone | RORER PHARMACEUTICAL CORPORATION (US) | 1989-08-22 | — | — | US | disclosed |
| WO-1988003025-A1 | HETEROCYCLIC SUBSTITUTED BICYCLOUREAS HAVING CARDIOTONIC ACTIVITY | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1988-05-05 | — | — | WO | disclosed |