Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412408 | 0.79 | ITGB3 (0.61) | LMNATSHRF10ITGB3ITGA2B | |
| SCHEMBL7412411 | 0.79 | ITGB3 (0.61) | LMNATSHRF10ITGB3ITGA2B | |
| SCHEMBL7418544 | 0.78 | LMNA (0.38) | LMNATSHRCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4779824 | 0.70 | LMNA (0.59) | LMNATSHRCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL27742525 | 0.70 | LMNA (0.59) | LMNATSHRCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4780175 | 0.69 | LMNA (0.57) | LMNATSHRCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7418987 | 0.68 | LMNA (0.41) | LMNATSHRCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7421017 | 0.68 | ITGB3 (0.61) | F10ITGB3ITGA2B | |
| SCHEMBL7422860 | 0.68 | ITGB3 (0.61) | F10ITGB3ITGA2B | |
| SCHEMBL6011851 | 0.67 | KIF11 (0.44) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552431-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-09-03 | — | — | US | disclosed |
| US-5424334-A | Peptide mimetic compounds useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-06-13 | — | — | US | disclosed |
| WO-1993012074-A1 | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-06-24 | — | — | WO | disclosed |