Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.59 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylamine SCHEMBL10458178 | 0.85 | LOXL2 (0.56) | SMN1; SMN2TAAR1LOXL2POLBL3MBTL1 | |
| Phenethylamine SCHEMBL27825144 | 0.82 | HTR2A (0.80) | HTR2ASMN1; SMN2TAAR1CYP2A6LOXL2 | |
| Phenethylamine SCHEMBL31547322 | 0.82 | HTR2A (0.80) | HTR2ASMN1; SMN2TAAR1CYP2A6LOXL2 | |
| SCHEMBL7814243 | 0.80 | POLB (0.54) | SMN1; SMN2POLBL3MBTL1S1PR1S1PR5 | |
| Phenethylamine SCHEMBL8618614 | 0.80 | HTR2A (0.76) | HTR2ASMN1; SMN2TAAR1CYP2A6LOXL2 | |
| Phenethylamine SCHEMBL27723601 | 0.80 | HTR2A (0.76) | HTR2ASMN1; SMN2TAAR1CYP2A6LOXL2 | |
| Phenethylamine SCHEMBL29010601 | 0.80 | HTR2A (0.76) | HTR2ASMN1; SMN2TAAR1CYP2A6LOXL2 | |
| Phenethylamine SCHEMBL27818452 | 0.79 | HTR2A (0.67) | HTR2ASMN1; SMN2TAAR1CYP2A6LOXL2 | |
| Phenethylamine SCHEMBL11321112 | 0.78 | TAAR1 (0.73) | HTR2ASMN1; SMN2TAAR1CYP2A6LOXL2 | |
| Phenethylamine SCHEMBL27806571 | 0.78 | TAAR1 (0.73) | HTR2ASMN1; SMN2TAAR1CYP2A6LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0349570-A1 | RENIN INHIBITORS CONTAINING A CYCLOPROPYL AMINO ACID AND/OR A CYCLOALKYL TRANSITION-STATE ANALOGUE | THE UPJOHN COMPANY (US) | 1990-01-10 | — | — | EP | disclosed |
| WO-1988007053-A1 | RENIN INHIBITORS CONTAINING A CYCLOPROPYL AMINO ACID AND/OR A CYCLOALKYL TRANSITION-STATE ANALOGUE | THE UPJOHN COMPANY (US) | 1988-09-22 | — | — | WO | disclosed |