Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | BMP1 | P13497 | 4/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.31 |
| ▸ | NPPA | P01160 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421752 | 0.82 | MEN1 (0.39) | BCHEMEN1KMT2ABMP1OPRM1 | |
| SCHEMBL7420461 | 0.80 | BCHE (0.37) | BCHEMEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL5869917 | 0.79 | NPPA (0.42) | BCHEMEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL8255171 | 0.79 | NPPA (0.42) | BCHEMEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL7418500 | 0.77 | BCHE (0.38) | BCHEMEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL7425447 | 0.76 | DHFR (0.34) | MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL7425815 | 0.76 | GRN (0.43) | ALDH1A1MAPK1C3AR1 | |
| SCHEMBL5869416 | 0.75 | NPPA (0.40) | BCHEMEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL8249944 | 0.75 | NPPA (0.40) | BCHEMEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL7417318 | 0.73 | CNR2 (0.40) | ALDH1A1CNR2NPPAMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |