Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.37 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418128 | 0.82 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL7415863 | 0.80 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL7422043 | 0.78 | AGTR1 (0.40) | AGTR1 | |
| SCHEMBL243577 | 0.76 | AGTR2 (0.37) | AGTR1AGTR2 | |
| SCHEMBL240032 | 0.74 | OPRM1 (0.39) | — | |
| SCHEMBL7423304 | 0.73 | PDE4A (0.38) | AGTR1AGTR2 | |
| SCHEMBL244149 | 0.72 | OPRM1 (0.37) | — | |
| SCHEMBL9685865 | 0.71 | AGTR1 (0.51) | AGTR1AGTR2GP6 | |
| SCHEMBL241111 | 0.71 | AGTR2 (0.43) | AGTR1AGTR2 | |
| SCHEMBL2884118 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789415-A | Azacyclic-heterocyclic compounds as angiotension II receptor antagonists | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| WO-1995002596-A1 | AZACYCLIC-HETEROCYCLIC COMPOUNDS AS ANGIOTENSIN II RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1995-01-26 | — | — | WO | disclosed |