Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 11/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.36 |
| ▸ | OXTR | P30559 | 3/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.30 |
| ▸ | SMO | Q99835 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423883 | 0.82 | NFKB1 (0.42) | AVPR2AVPR1AOXTRHCRTR1HCRTR2 | |
| SCHEMBL7638228 | 0.78 | AVPR2 (0.57) | AVPR2AVPR1AOXTR | |
| SCHEMBL6624608 | 0.76 | AVPR2 (0.61) | AVPR2AVPR1AOXTR | |
| SCHEMBL6623658 | 0.75 | AVPR2 (0.55) | AVPR2AVPR1AOXTR | |
| SCHEMBL7632997 | 0.70 | AVPR2 (0.41) | AVPR2AVPR1AOXTR | |
| SCHEMBL7417501 | 0.69 | AVPR2 (0.40) | AVPR2AVPR1AOXTRHCRTR1HCRTR2 | |
| SCHEMBL7582976 | 0.69 | AVPR2 (0.42) | AVPR2AVPR1AOXTR | |
| SCHEMBL7421267 | 0.68 | AVPR2 (0.38) | AVPR2AVPR1AOXTR | |
| SCHEMBL7422025 | 0.68 | AVPR2 (0.42) | AVPR2AVPR1AOXTRKDM4E | |
| SCHEMBL7422271 | 0.67 | AVPR2 (0.52) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000062-A1 | TRICYCLIC VASOPRESSIN AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-05-17 | — | — | EP | claimed |
| WO-1999006409-A1 | TRICYCLIC VASOPRESSIN AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-02-11 | — | — | WO | claimed |