Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 13/20 | 0.42 |
| ▸ | JUN | P05412 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | XPO1 | O14980 | 4/20 | 0.42 |
| ▸ | ATF1 | P18846 | 12/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419308 | 0.82 | AVPR2 (0.44) | AVPR2OXTRAVPR1AHCRTR1HCRTR2 | |
| SCHEMBL7421267 | 0.77 | AVPR2 (0.38) | AVPR2OXTRAVPR1A | |
| SCHEMBL7421754 | 0.77 | AVPR2 (0.50) | AVPR2OXTRAVPR1A | |
| SCHEMBL7417501 | 0.75 | AVPR2 (0.40) | AVPR2OXTRAVPR1AHCRTR1HCRTR2 | |
| SCHEMBL7420622 | 0.75 | AVPR2 (0.43) | AVPR2OXTRAVPR1A | |
| SCHEMBL7422025 | 0.73 | AVPR2 (0.42) | AVPR2OXTRAVPR1A | |
| SCHEMBL2313462 | 0.71 | HSD17B3 (0.32) | — | |
| SCHEMBL7549935 | 0.71 | BCAT2 (0.34) | AVPR2OXTRAVPR1A | |
| SCHEMBL7422271 | 0.71 | AVPR2 (0.52) | AVPR2OXTRAVPR1A | |
| SCHEMBL7424272 | 0.71 | AVPR2 (0.50) | AVPR2OXTRAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216045-A2 | VASOPRESSIN AGONIST FORMULATION AND PROCESS | American Cynamid Company (US) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001022969-A2 | VASOPRESSIN AGONIST FORMULATION AND PROCESS | AMERICAN CYNAMID COMPANY (US) | 2001-04-05 | — | — | WO | disclosed |
| EP-1000062-A1 | TRICYCLIC VASOPRESSIN AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999006409-A1 | TRICYCLIC VASOPRESSIN AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-02-11 | — | — | WO | disclosed |