Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 13/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 16/20 | 0.47 |
| ▸ | PDE4A | P27815 | 12/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420334 | 0.77 | PDE4D (0.68) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL5026485 | 0.72 | PDE4B (0.48) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL720382 | 0.72 | PDE4D (0.62) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL14364571 | 0.71 | PDE4B (0.45) | PDE4DPDE4BPDE4APDE4CP2RX7 | |
| SCHEMBL5022381 | 0.71 | PDE4D (0.53) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL2518442 | 0.69 | PDE4D (0.47) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL5794099 | 0.69 | PDE4D (0.65) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL2518447 | 0.69 | PDE4D (0.66) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL18929964 | 0.69 | TDP1 (0.55) | — | |
| SCHEMBL6470722 | 0.68 | PDE4B (0.46) | PDE4DPDE4BPDE4APDE4CP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995004046-A1 | COMPOUNDS AS PDE IV AND TNF INHIBITORS | RHONE-POULENC RORER LIMITED (GB) | 1995-02-09 | — | — | WO | disclosed |