SCHEMBL7419396

SCHEMBL7419396

[CH2]C(=O)NCC[N+]1([O-])CCCC1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TERT O14746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7421952 0.83 SMN1; SMN2 (0.30)
SCHEMBL7415079 0.80 KDM4E (0.41) TERT
SCHEMBL15266180 0.69 LMNA (0.54)
SCHEMBL9413480 0.68 BBOX1 (0.50) TERT
SCHEMBL7415076 0.65
SCHEMBL4557294 0.64 BBOX1 (0.33) TERT
SCHEMBL10642189 0.64 TERT (0.31) TERT
SCHEMBL3189969 0.64 BBOX1 (0.45) TERT
SCHEMBL3028238 0.64 TERT (0.35) TERT
SCHEMBL11048732 0.63 BBOX1 (0.41) TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0861249-A1 SUBSTITUTED SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1998-09-02 EP claimed
WO-1997018205-A1 SUBSTITUTED SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1997-05-22 WO claimed