Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 4/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | GLA | P06280 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409129 | 0.85 | HTR4 (0.40) | KDM4EALDH1A1GAAABL1ACHE | |
| SCHEMBL7413113 | 0.85 | SMN1; SMN2 (0.42) | KDM4EGLASMN1; SMN2 | |
| SCHEMBL14382462 | 0.79 | KDM4E (0.43) | KDM4EALDH1A1SOS1POLBGAA | |
| SCHEMBL7410564 | 0.79 | KDM4E (0.43) | KDM4EALDH1A1NPC1RAB9ATDP1 | |
| SCHEMBL7417517 | 0.78 | HTR4 (0.42) | KDM4EALDH1A1POLBGAAABL1 | |
| SCHEMBL7410791 | 0.78 | KDM4E (0.36) | KDM4EALDH1A1NPC1RAB9ATDP1 | |
| SCHEMBL6777423 | 0.76 | KDM4E (0.43) | KDM4EALDH1A1POLBNPC1RAB9A | |
| SCHEMBL7409675 | 0.76 | ALDH1A1 (0.37) | KDM4EALDH1A1NPC1RAB9ATDP1 | |
| SCHEMBL7417661 | 0.75 | HTR4 (0.39) | KDM4EALDH1A1POLBNPC1RAB9A | |
| SCHEMBL7414100 | 0.74 | GAA (0.33) | KDM4EALDH1A1NPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935511-A | Nervous system, gastrointestinal disorders | RORER PHARMACEUTICAL CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |