Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419491 | 1.00 | SYK (0.52) | SYKALDH1A1POLBCTSBMAPK1 | |
| SCHEMBL4633702 | 0.86 | CTSK (0.47) | SYKALDH1A1POLBCTSBMAPK1 | |
| SCHEMBL7418023 | 0.86 | CTSK (0.47) | SYKALDH1A1POLBCTSBMAPK1 | |
| SCHEMBL5497072 | 0.86 | CTSK (0.47) | SYKALDH1A1POLBCTSBMAPK1 | |
| SCHEMBL5187344 | 0.83 | CTSK (0.47) | SYKALDH1A1POLBCTSBMAPK1 | |
| SCHEMBL7370167 | 0.83 | SYK (0.44) | SYKALDH1A1POLBCTSBMAPK1 | |
| SCHEMBL5188450 | 0.83 | CTSK (0.47) | SYKALDH1A1POLBCTSBMAPK1 | |
| SCHEMBL28014675 | 0.83 | SYK (0.47) | SYKALDH1A1POLBMAPK1L3MBTL1 | |
| SCHEMBL7420417 | 0.82 | L3MBTL1 (0.47) | SYKALDH1A1POLBMAPK1L3MBTL1 | |
| SCHEMBL7369332 | 0.82 | POLB (0.49) | SYKALDH1A1POLBCTSBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0641323-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| WO-1994021612-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |