Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5008265 | 0.85 | KMT2A (0.56) | MEN1KMT2AALDH1A1PKMGAA | |
| SCHEMBL194837 | 0.82 | MEN1 (0.54) | MEN1KMT2AALDH1A1PKMGAA | |
| SCHEMBL5012151 | 0.75 | FAAH (0.61) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL888411 | 0.75 | KDM4E (0.56) | ALDH1A1GAAMAPTKDM4EL3MBTL1 | |
| SCHEMBL2741813 | 0.75 | MEN1 (0.47) | MEN1KMT2AALDH1A1PKMGAA | |
| SCHEMBL29609117 | 0.74 | KDM4E (0.59) | ALDH1A1GAAMAPTKDM4EL3MBTL1 | |
| SCHEMBL2125695 | 0.74 | KDM4E (0.59) | ALDH1A1GAAMAPTKDM4EL3MBTL1 | |
| SCHEMBL9279836 | 0.74 | GAA (0.63) | MEN1KMT2AALDH1A1PKMGAA | |
| SCHEMBL7006424 | 0.74 | CA9 (0.46) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL9562315 | 0.74 | GAA (0.54) | ALDH1A1GAAMAPTKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255735-A2 | PYRIDINE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-11-13 | — | — | EP | claimed |
| WO-2001056990-A2 | PYRIDINE DERIVATES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2001-08-09 | — | — | WO | claimed |