Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5008265 | 0.87 | KMT2A (0.56) | MEN1KMT2AALDH1A1PKMCYP2C19 | |
| SCHEMBL7419655 | 0.82 | MEN1 (0.55) | MEN1KMT2AALDH1A1PKMCYP2C19 | |
| SCHEMBL2442810 | 0.78 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1PKMGAA | |
| SCHEMBL2741813 | 0.77 | MEN1 (0.47) | MEN1KMT2AALDH1A1PKMCYP2C19 | |
| SCHEMBL1697611 | 0.74 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1PKMGAA | |
| SCHEMBL29814681 | 0.74 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1PKMGAA | |
| SCHEMBL613534 | 0.73 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1PKMGAA | |
| SCHEMBL5008269 | 0.73 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1PKMGAA | |
| SCHEMBL5013443 | 0.73 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1PKMGAA | |
| SCHEMBL2125695 | 0.73 | KDM4E (0.59) | ALDH1A1GAAKDM4EMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252939-B2 | Sulfoximinamide compounds for combating animal pests | BASF SE (DE) | 2012-08-28 | — | — | US | disclosed |
| EP-2307370-B1 | SULFOXIMINAMIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2012-01-04 | — | — | EP | disclosed |
| US-20110306493-A1 | Sulfoximinamide Compounds for Combating Animal Pests | BASF SE (DE) | 2011-12-15 | — | — | US | disclosed |
| EP-2307370-A1 | SULFOXIMINAMIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009156336-A1 | SULFOXIMINAMIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2009-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306493-A1 | Sulfoximinamide Compounds for Combating Animal Pests | PRDX1, PRDX2, PRDX4 | MEN1 1908/4885KMT2A 1250/4885ALDH1A1 2259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.