Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7418337 | 0.84 | CTSS (0.40) | CTSSCTSL | |
| SCHEMBL7675072 | 0.81 | CTSS (0.42) | CTSSCTSL | |
| SCHEMBL7013068 | 0.80 | CTSS (0.48) | CTSSCTSL | |
| Hydrochloric Acid SCHEMBL7419368 | 0.80 | CTSS (0.48) | CTSSCTSL | |
| SCHEMBL7417604 | 0.78 | EPHX1 (0.33) | CTSSCTSL | |
| SCHEMBL5361059 | 0.76 | CTSS (0.60) | CTSSCTSL | |
| Hydrochloric Acid SCHEMBL5361278 | 0.75 | CTSS (0.59) | CTSSCTSL | |
| SCHEMBL8296552 | 0.74 | CTSS (0.45) | CTSSCTSL | |
| SCHEMBL8296548 | 0.72 | CTSS (0.42) | CTSSCTSL | |
| SCHEMBL5125202 | 0.67 | CNR1 (0.41) | CTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218372-A1 | NOVEL SPIROHETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | Boehringer Ingelheim Pharmaceuticals, Inc. (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001019816-A1 | NOVEL SPIROHETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-03-22 | — | — | WO | disclosed |