Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 9/20 | 0.48 |
| ▸ | CTSL | P07711 | 5/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7418337 | 0.91 | CTSS (0.40) | CTSSCTSLEPHX1 | |
| SCHEMBL7419722 | 0.80 | CTSS (0.47) | CTSSCTSL | |
| SCHEMBL7417604 | 0.78 | EPHX1 (0.33) | CTSSCTSLEPHX1 | |
| SCHEMBL7675072 | 0.77 | CTSS (0.42) | CTSSCTSLEPHX1 | |
| SCHEMBL5363252 | 0.77 | CTSS (0.60) | CTSSCTSL | |
| SCHEMBL23462315 | 0.73 | CTSS (0.45) | CTSSCTSLEPHX1 | |
| SCHEMBL6971904 | 0.69 | CTSS (0.52) | CTSSCTSL | |
| SCHEMBL23462427 | 0.69 | CTSS (0.42) | CTSSCTSL | |
| SCHEMBL8296552 | 0.69 | CTSS (0.45) | CTSSCTSL | |
| Hydrochloric Acid SCHEMBL5367945 | 0.68 | CTSS (0.51) | CTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003529546-A | — | — | 2003-10-07 | — | — | JP | claimed |
| EP-1218372-A1 | NOVEL SPIROHETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | Boehringer Ingelheim Pharmaceuticals, Inc. (US) | 2002-07-03 | — | — | EP | claimed |
| WO-2001019816-A1 | NOVEL SPIROHETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-03-22 | — | — | WO | claimed |
| EP-1218372-A1 | NOVEL SPIROHETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | Boehringer Ingelheim Pharmaceuticals, Inc. (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001019816-A1 | NOVEL SPIROHETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-03-22 | — | — | WO | disclosed |