Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
| ▸ | GPX4 | P36969 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | CCKAR | P32238 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5078340 | 0.93 | CNR2 (0.38) | DRD2DRD3KMT2AMEN1RAB9A | |
| SCHEMBL5077622 | 0.86 | KMT2A (0.50) | DRD2DRD3KMT2AMEN1RAB9A | |
| SCHEMBL6011590 | 0.85 | DRD2 (0.36) | DRD2DRD3RAB9ACACNA1GTHRB | |
| SCHEMBL5081549 | 0.84 | P2RX7 (0.44) | DRD2DRD3KMT2AMEN1CACNA1G | |
| SCHEMBL5078966 | 0.84 | CACNA1G (0.42) | DRD2DRD3KMT2ACACNA1GTP53 | |
| SCHEMBL5078910 | 0.84 | F10 (0.45) | KMT2AMEN1 | |
| SCHEMBL5078299 | 0.84 | AKR1C3 (0.44) | DRD2DRD3KMT2ACACNA1G | |
| SCHEMBL5075698 | 0.84 | NAMPT (0.40) | DRD2DRD3KMT2ACACNA1GTP53 | |
| SCHEMBL5078283 | 0.83 | DRD2 (0.42) | DRD2DRD3KMT2AMEN1RAB9A | |
| SCHEMBL5075654 | 0.82 | CHEK2 (0.41) | DRD3GPX4OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112251-A1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015609-A1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA S.A. (FR) | 2000-03-23 | — | — | WO | disclosed |