Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 19/20 | 0.49 |
| ▸ | TPSD1 | Q9BZJ3 | 19/20 | 0.49 |
| ▸ | TPSG1 | Q9NRR2 | 19/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474183 | 0.79 | TPSAB1 (0.56) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL16467967 | 0.72 | HSD11B1 (0.48) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL8275268 | 0.72 | TPSAB1 (0.51) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7422621 | 0.71 | TPSAB1 (0.67) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL12991729 | 0.70 | HSD11B1 (0.52) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL28206534 | 0.70 | HSD11B1 (0.52) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL13016393 | 0.70 | HSD11B1 (0.52) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL16468337 | 0.68 | TPSAB1 (0.47) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL12791455 | 0.67 | HSD11B1 (0.47) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL25889068 | 0.66 | HSD11B1 (0.50) | TPSAB1TPSD1TPSG1PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782571-A1 | COMPOSITIONS AND METHODS FOR TREATING MAST-CELL INFLAMMATORY CONDITION | ARRIS PHARMACEUTICAL CORPORATION (US) | 1997-07-09 | — | — | EP | claimed |
| WO-1996009297-A1 | COMPOSITIONS AND METHODS FOR TREATING MAST-CELL INFLAMMATORY CONDITION | ARRIS PHARMACEUTICAL CORPORATION (US) | 1996-03-28 | — | — | WO | claimed |