Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | CPA2 | P48052 | 1/20 | 0.44 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 10/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | VHL | P40337 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene SCHEMBL8412145 | 0.93 | OPRM1 (0.42) | KMT2ACTRB1TACR1CMA1ACE | |
| SCHEMBL7419961 | 0.84 | CASP1 (0.60) | KMT2ATACR1CASP1 | |
| Naphthalene SCHEMBL7416123 | 0.80 | CASP3 (0.49) | CASP1 | |
| Naphthalene SCHEMBL7419594 | 0.79 | CASP1 (0.50) | CASP1 | |
| Naphthalene SCHEMBL8412953 | 0.78 | CASP3 (0.48) | CASP1 | |
| Naphthalene SCHEMBL8414632 | 0.78 | CASP3 (0.48) | CASP1 | |
| Naphthalene SCHEMBL7413352 | 0.78 | CASP3 (0.48) | CASP1 | |
| Naphthalene SCHEMBL8061774 | 0.78 | CASP1 (0.44) | CASP1 | |
| SCHEMBL30799597 | 0.77 | ITGB1 (0.51) | CPA1CPA2CPA4KMT2ATACR1 | |
| Naphthalene SCHEMBL7415860 | 0.77 | CASP1 (0.54) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001019373-A2 | METHODS AND COMPOSITIONS FOR MODULATING RESPONSIVENESS TO CORTICOSTEROIDS | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-22 | — | — | WO | disclosed |
| EP-0932598-A1 | ASPARTATE ESTER INHIBITORS OF INTERLEUKIN-1$g(b) CONVERTING ENZYME | WARNER-LAMBERT COMPANY (US) | 1999-08-04 | — | — | EP | disclosed |
| WO-1998016502-A1 | ASPARTATE ESTER INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME | WARNER-LAMBERT COMPANY (US) | 1998-04-23 | — | — | WO | disclosed |