Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 5/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717975 | 0.91 | SLC18A2 (0.39) | L3MBTL1SLC6A4 | |
| SCHEMBL7414244 | 0.91 | SLC18A2 (0.39) | L3MBTL1SLC6A4 | |
| SCHEMBL7422049 | 0.90 | SLC6A3 (0.45) | — | |
| Hydrochloric Acid SCHEMBL8720630 | 0.90 | SLC18A2 (0.38) | L3MBTL1 | |
| SCHEMBL7424654 | 0.90 | SLC6A3 (0.45) | — | |
| SCHEMBL7424665 | 0.90 | SLC6A3 (0.45) | — | |
| SCHEMBL7418030 | 0.89 | KDM2B (0.39) | L3MBTL1 | |
| SCHEMBL7416044 | 0.89 | SLC6A5 (0.46) | L3MBTL1SLC6A4 | |
| SCHEMBL26790183 | 0.89 | SLC6A5 (0.46) | L3MBTL1SLC6A4 | |
| SCHEMBL7416049 | 0.89 | SLC6A5 (0.46) | L3MBTL1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558487-B1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1998-10-07 | — | — | EP | disclosed |
| US-5328917-A | Aminoalkyl and phenyl substituted hydrogenated pyridines | NOVO NORDISK A/S (DK) | 1994-07-12 | — | — | US | disclosed |
| EP-0558487-A1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992001672-A1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-02-06 | — | — | WO | disclosed |