Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424654 | 1.00 | SLC6A3 (0.45) | SLC6A3SIGMAR1HRH3 | |
| SCHEMBL7422049 | 1.00 | SLC6A3 (0.45) | SLC6A3SIGMAR1HRH3 | |
| SCHEMBL8717975 | 0.91 | SLC18A2 (0.39) | SIGMAR1HRH3 | |
| SCHEMBL7414244 | 0.91 | SLC18A2 (0.39) | SIGMAR1HRH3 | |
| Hydrochloric Acid SCHEMBL8720630 | 0.90 | SLC18A2 (0.38) | SIGMAR1HRH3 | |
| SCHEMBL7419970 | 0.90 | L3MBTL1 (0.45) | — | |
| SCHEMBL8722858 | 0.89 | KDM4E (0.42) | SLC6A3SIGMAR1HRH3 | |
| SCHEMBL8722860 | 0.89 | KDM4E (0.42) | SLC6A3SIGMAR1HRH3 | |
| SCHEMBL8718276 | 0.89 | KDM4E (0.42) | SLC6A3SIGMAR1HRH3 | |
| SCHEMBL8718292 | 0.89 | HRH3 (0.49) | SIGMAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558487-B1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1998-10-07 | — | — | EP | claimed |
| EP-0558487-A1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-09-08 | — | — | EP | claimed |
| WO-1992001672-A1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-02-06 | — | — | WO | claimed |