Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419979 | 1.00 | DPP4 (0.43) | DPP4HRH3MAPK1ALDH1A1KMT2A | |
| SCHEMBL12898939 | 0.87 | ALDH1A1 (0.38) | DPP4HRH3ALDH1A1KMT2A | |
| SCHEMBL7839758 | 0.86 | DPP4 (0.42) | DPP4HRH3MAPK1OPRM1OPRD1 | |
| SCHEMBL7364324 | 0.83 | DPP4 (0.32) | DPP4HRH3OPRM1OPRD1 | |
| SCHEMBL25684409 | 0.83 | MAPK1 (0.37) | HRH3MAPK1KMT2AMEN1TSHR | |
| SCHEMBL7023702 | 0.82 | S1PR3 (0.48) | ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL30899827 | 0.82 | ALDH1A1 (0.34) | DPP4ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL30899830 | 0.82 | ALDH1A1 (0.34) | DPP4ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL30899856 | 0.82 | ALDH1A1 (0.34) | DPP4ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL12034086 | 0.81 | L3MBTL1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |