Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | PDE9A | O76083 | 4/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12872135 | 0.76 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1PDE9APDE1C | |
| SCHEMBL7418070 | 0.74 | ALDH1A1 (0.42) | KMT2AMEN1ALDH1A1NPSR1GAA | |
| SCHEMBL10927968 | 0.69 | ALDH1A1 (0.50) | KMT2AMAOAMAOBALDH1A1CYP2A6 | |
| SCHEMBL7636229 | 0.67 | GRIA1 (0.52) | MAOAMAOBALDH1A1CYP2A6PDE9A | |
| SCHEMBL9042248 | 0.66 | LRRK2 (0.43) | MAOAMAOBERBB2ALDH1A1CYP2A6 | |
| SCHEMBL10896760 | 0.63 | ALDH1A1 (0.42) | MAOAMAOBALDH1A1CYP2A6 | |
| SCHEMBL21950248 | 0.63 | KDM4E (0.42) | KMT2AMAPK1HSD17B10MEN1MAOA | |
| SCHEMBL1046307 | 0.62 | AHR (0.54) | KMT2AHSD17B10MEN1ALDH1A1KDM4E | |
| SCHEMBL20904470 | 0.62 | AHR (0.42) | KMT2AHSD17B10MEN1ALDH1A1KDM4E | |
| SCHEMBL1047283 | 0.62 | PBRM1 (0.42) | KMT2AHSD17B10MEN1ALDH1A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016071-A1 | HETEROCYCLIC DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-19 | — | — | WO | disclosed |