Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP7 | P09237 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP14 | P50281 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | AGXT | P21549 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4952656 | 0.87 | CA2 (0.58) | CA2CA9CA1MMP9APLNR | |
| SCHEMBL5937187 | 0.84 | APLNR (0.59) | CA2CA9CA1APLNRIDO1 | |
| SCHEMBL3838706 | 0.81 | STS (0.63) | CA2CA9CA1PPARGMMP2 | |
| SCHEMBL19845815 | 0.81 | CA2 (0.52) | CA2CA9CA1MMP9APLNR | |
| SCHEMBL20743498 | 0.81 | NQO1 (0.52) | CA2CA9CA1ALDH1A1CA12 | |
| SCHEMBL979920 | 0.81 | PPARA (0.49) | CA2CA9CA1PPARGMMP2 | |
| SCHEMBL7167112 | 0.80 | CA2 (0.39) | CA2CA9CA1MMP2MMP7 | |
| SCHEMBL575589 | 0.80 | CA2 (0.52) | CA2CA9CA1MMP2MMP7 | |
| SCHEMBL24041811 | 0.79 | PPARG (0.40) | CA2CA9CA1PPARGMMP2 | |
| SCHEMBL2254857 | 0.79 | POLB (0.50) | CA2CA9CA1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116194439-A | SOCE inhibitors and therapeutic uses thereof | 国家医疗保健研究所 | 2023-05-30 | — | — | CN | disclosed |
| EP-4157822-A1 | SOCE INHIBITORS AND THERAPEUTIC USES THEREOF | Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) | 2023-04-05 | — | — | EP | disclosed |
| WO-2021233994-A1 | SOCE INHIBITORS AND THERAPEUTIC USES THEREOF | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2021-11-25 | — | — | WO | disclosed |
| EP-3912972-A1 | SOCE INHIBITORS AND THERAPEUTIC USES THEREOF | Centre Hospitalier Régional et Universitaire de Brest (FR) | 2021-11-24 | — | — | EP | disclosed |
| WO-1996036595-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | disclosed |