Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL747058 | 0.78 | KDM4E (0.60) | L3MBTL1HDAC6PKMKDM4EGRIN2B | |
| SCHEMBL27626566 | 0.73 | GRIN2B (0.54) | L3MBTL1HDAC6PKMKDM4EGRIN2B | |
| Hydrochloric Acid SCHEMBL7668684 | 0.71 | MEN1 (0.49) | L3MBTL1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8981264 | 0.70 | MEN1 (0.50) | L3MBTL1CYP3A4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7868066 | 0.69 | ANPEP (0.66) | L3MBTL1HDAC6PKMKDM4ECYP1A2 | |
| SCHEMBL4655422 | 0.69 | MEN1 (0.49) | L3MBTL1CYP3A4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28086104 | 0.69 | ITGB3 (0.51) | L3MBTL1CYP3A4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL24064998 | 0.69 | MEN1 (0.46) | L3MBTL1CYP3A4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7382201 | 0.69 | ANPEP (0.71) | L3MBTL1HDAC6PKMKDM4ESMN1; SMN2 | |
| SCHEMBL23318030 | 0.68 | MBOAT4 (0.55) | L3MBTL1CYP3A4SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019386-A1 | REVERSE HYDROXAMATE DERIVATIVES AS METALLOPROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998038179-A1 | REVERSE HYDROXAMATE DERIVATIVES AS METALLOPROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1998-09-03 | — | — | WO | disclosed |