Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 13/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326043 | 0.86 | PDE4B (0.49) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL7357352 | 0.81 | PDE4B (0.53) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL7327409 | 0.80 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7361049 | 0.79 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL7420754 | 0.78 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL7363845 | 0.77 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL7359135 | 0.76 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL7423009 | 0.76 | PDE4D (0.76) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6889943 | 0.75 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27537534 | 0.75 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557408-A4 | IMIDAZOLIDINONE COMPOUNDS | — | 1993-10-27 | — | — | EP | disclosed |
| EP-0557408-A1 | IMIDAZOLIDINONE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-09-01 | — | — | EP | disclosed |
| WO-1992007567-A1 | IMIDAZOLIDINONE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-05-14 | — | — | WO | disclosed |