Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 15/20 | 0.38 |
| ▸ | CTSS | P25774 | 15/20 | 0.38 |
| ▸ | CTSK | P43235 | 15/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6589398 | 1.00 | CTSL (0.38) | CTSLCTSSCTSKALDH1A1CYP3A4 | |
| SCHEMBL6592004 | 0.90 | CTSL (0.37) | CTSLCTSSCTSKNAAA | |
| SCHEMBL7418471 | 0.90 | CTSL (0.37) | CTSLCTSSCTSKNAAA | |
| SCHEMBL6590297 | 0.89 | CYP3A4 (0.34) | ALDH1A1CYP3A4CYP2C9CYP2C19NAAA | |
| SCHEMBL7413329 | 0.89 | CYP3A4 (0.34) | ALDH1A1CYP3A4CYP2C9CYP2C19NAAA | |
| SCHEMBL6586151 | 0.89 | ALDH1A1 (0.31) | CTSLCTSSCTSKALDH1A1CYP3A4 | |
| SCHEMBL6590839 | 0.84 | CTSL (0.39) | CTSLCTSSCTSK | |
| SCHEMBL7411727 | 0.84 | CTSL (0.39) | CTSLCTSSCTSK | |
| SCHEMBL7412268 | 0.81 | CTSL (0.39) | CTSLCTSSCTSK | |
| SCHEMBL6093202 | 0.81 | CTSL (0.39) | CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002544274-A | — | — | 2002-12-24 | — | — | JP | claimed |
| EP-1178986-A2 | FURANONE DERIVATIVES AS INHIBITORS OF CATHEPSIN S | Medivir UK Ltd (GB) | 2002-02-13 | — | — | EP | claimed |
| WO-2000069855-A2 | FURANONE DERIVATIVES AS INHIBITORS OF CATHEPSIN S | MEDIVIR UK LIMITED (GB) | 2000-11-23 | — | — | WO | claimed |
| EP-1178986-A2 | FURANONE DERIVATIVES AS INHIBITORS OF CATHEPSIN S | Medivir UK Ltd (GB) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000069855-A2 | FURANONE DERIVATIVES AS INHIBITORS OF CATHEPSIN S | MEDIVIR UK LIMITED (GB) | 2000-11-23 | — | — | WO | disclosed |