Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5002884 | 0.88 | KDM4E (0.33) | KDM4EALDH1A1POLBCHRM5CHRM3 | |
| SCHEMBL5002525 | 0.79 | KDM4E (0.39) | KDM4EALDH1A1POLBMAPTGAA | |
| SCHEMBL13992732 | 0.76 | PPARD (0.40) | CHRM5CHRM3SMN1; SMN2ANPEPERAP2 | |
| SCHEMBL7419651 | 0.72 | ANPEP (0.38) | ANPEPERAP2 | |
| SCHEMBL7453394 | 0.69 | MAPT (0.50) | POLBCHRM5CHRM3SMN1; SMN2ANPEP | |
| SCHEMBL776263 | 0.69 | LAP3 (0.36) | ALDH1A1 | |
| SCHEMBL336756 | 0.69 | MAPT (0.50) | POLBCHRM5CHRM3SMN1; SMN2ANPEP | |
| SCHEMBL9041381 | 0.68 | MAPT (0.49) | POLBCHRM5CHRM3SMN1; SMN2ANPEP | |
| SCHEMBL8393831 | 0.68 | MAPT (0.49) | POLBCHRM5CHRM3SMN1; SMN2ANPEP | |
| Hydrochloric Acid SCHEMBL31341457 | 0.68 | MAPT (0.49) | KDM4EPOLBCHRM5CHRM3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815103-A1 | TRYPSIN AND THROMBIN INHIBITORS | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029327-A1 | TRYPSIN AND THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |