Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | CPN1 | P15169 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.30 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7422701 | 0.79 | GNAO1 (0.39) | GNAI3GNAO1GNAI1 | |
| SCHEMBL3979978 | 0.75 | — | — | |
| SCHEMBL4990902 | 0.72 | ALDH1A1 (0.32) | — | |
| SCHEMBL7420965 | 0.72 | KDM4E (0.38) | ANPEPERAP2 | |
| SCHEMBL1251447 | 0.72 | PPARD (0.35) | — | |
| SCHEMBL2118428 | 0.70 | LAP3 (0.38) | ANPEP | |
| SCHEMBL776263 | 0.69 | LAP3 (0.36) | — | |
| SCHEMBL3187918 | 0.69 | MEN1 (0.52) | ANPEPERAP2CPN1CPB2 | |
| Hydrochloric Acid SCHEMBL13269112 | 0.69 | LAP3 (0.37) | ANPEP | |
| SCHEMBL11745106 | 0.68 | LAP3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815103-A1 | TRYPSIN AND THROMBIN INHIBITORS | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029327-A1 | TRYPSIN AND THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |