Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.47 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 14/20 | 0.42 |
| ▸ | PYGM | P11217 | 10/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL740197 | 0.85 | SMYD3 (0.51) | SMYD3EHMT2PYGLPYGM | |
| SCHEMBL3342391 | 0.78 | F10 (0.53) | EHMT2F10 | |
| SCHEMBL4270766 | 0.78 | F10 (0.53) | EHMT2F10 | |
| SCHEMBL3342385 | 0.78 | F10 (0.53) | EHMT2F10 | |
| SCHEMBL4087543 | 0.78 | F10 (0.53) | EHMT2F10 | |
| SCHEMBL10476602 | 0.78 | F10 (0.53) | EHMT2F10 | |
| SCHEMBL739706 | 0.74 | KMT2A (0.50) | SMYD3PYGL | |
| SCHEMBL12507532 | 0.74 | SMYD3 (0.71) | SMYD3EHMT2PYGLPYGM | |
| SCHEMBL741538 | 0.74 | SMYD3 (0.46) | SMYD3PYGL | |
| SCHEMBL743763 | 0.74 | SMYD3 (0.46) | SMYD3PYGLF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431370-A1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-7935824-B2 | Ethylenediamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2011-05-03 | — | — | US | disclosed |