Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | PFKFB4 | Q16877 | 4/20 | 0.40 |
| ▸ | PFKFB3 | Q16875 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 2/20 | 0.35 |
| ▸ | HTR1B | P28222 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL742627 | 0.93 | HTR6 (0.56) | HTR6SLC2A1PFKFB4PFKFB3CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL741153 | 0.81 | HTR6 (0.52) | HTR6CYP3A4HTR2CHTR2A | |
| Trifluoroacetic Acid SCHEMBL743994 | 0.81 | HTR6 (0.46) | HTR6CYP3A4HTR2CHTR2A | |
| Trifluoroacetic Acid SCHEMBL741125 | 0.80 | SPR (0.33) | HTR6HTR2C | |
| Trifluoroacetic Acid SCHEMBL743160 | 0.79 | HTR2C (0.40) | HTR6CYP3A4HTR2CHTR2ADRD3 | |
| Trifluoroacetic Acid SCHEMBL743482 | 0.79 | HTR6 (0.34) | HTR6CYP3A4HTR2CHTR2A | |
| Trifluoroacetic Acid SCHEMBL744550 | 0.79 | HTR6 (0.39) | HTR6CYP3A4HTR2CHTR2A | |
| Trifluoroacetic Acid SCHEMBL744465 | 0.78 | HTR6 (0.46) | HTR6CYP3A4HTR2CHTR2A | |
| Trifluoroacetic Acid SCHEMBL741198 | 0.78 | HTR6 (0.36) | HTR6CYP3A4HTR2CHTR2ADRD3 | |
| Trifluoroacetic Acid SCHEMBL743912 | 0.77 | HTR6 (0.46) | HTR6CYP3A4HTR1DHTR1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138333-B2 | Sulfonyl-indole derivatives | PROXIMAGEN LIMITED (GB) | 2012-03-20 | — | — | US | disclosed |
| US-20080293694-A1 | New compounds | BIOVITRUM AB (PUBL.) (SE) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293694-A1 | New compounds | HTR6, HTR1A, HTR1B | HTR6 1/4885SLC2A1 1589/4885PFKFB4 1779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.