Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 2/20 | 0.37 |
| ▸ | STK10 | O94804 | 2/20 | 0.33 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 4/20 | 0.32 |
| ▸ | F2 | P00734 | 3/20 | 0.32 |
| ▸ | PRF1 | P14222 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422523 | 0.92 | MMP13 (0.33) | ALPL | |
| SCHEMBL7421981 | 0.90 | — | — | |
| SCHEMBL7420810 | 0.76 | F2 (0.33) | F10F2PRF1 | |
| SCHEMBL7426894 | 0.67 | F10 (0.44) | GHSRF10CYP2C9CYP2C19 | |
| SCHEMBL5491832 | 0.62 | MKNK1 (0.48) | GHSRF10F2CYP2D6CYP2A6 | |
| SCHEMBL7425048 | 0.61 | F10 (0.75) | F10F2 | |
| SCHEMBL7377260 | 0.60 | GHSR (0.36) | GHSRF10F2PRF1CYP2D6 | |
| SCHEMBL3472206 | 0.57 | KDM4E (0.48) | GHSRCYP2D6CYP2A6CYP2C9CYP2C19 | |
| SCHEMBL1069272 | 0.57 | AR (0.40) | ALPLCYP2A6 | |
| SCHEMBL8624162 | 0.57 | F10 (0.54) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894088-A4 | SUBSTITUTED SULFONIC ACID N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS | RHONE POULENC RORER PHARMA (US) | 2001-12-05 | — | — | EP | disclosed |
| EP-0894088-A1 | SUBSTITUTED SULFONIC ACID N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-02-03 | — | — | EP | disclosed |
| WO-1998024784-A1 | SUBSTITUTED SULFONIC ACID N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-06-11 | — | — | WO | disclosed |