Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 10/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 10/20 | 0.48 |
| ▸ | PSMB9 | P28065 | 9/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 9/20 | 0.48 |
| ▸ | PSMB10 | P40306 | 4/20 | 0.48 |
| ▸ | PSMB2 | P49721 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6556306 | 0.91 | ATM (0.54) | RENATMKLK5 | |
| SCHEMBL6556305 | 0.91 | ATM (0.54) | RENATMKLK5 | |
| SCHEMBL9081107 | 0.91 | REN (0.49) | RENATMKLK5 | |
| SCHEMBL9081020 | 0.90 | KLK5 (0.45) | PSMB1PSMB5PSMB9PSMB8PSMB10 | |
| SCHEMBL7331235 | 0.89 | BCL2 (0.55) | BCL2PSMB10PTPN1RENKLK5 | |
| SCHEMBL8945503 | 0.86 | REN (0.49) | BCL2PSMB1PSMB5PSMB9PSMB8 | |
| SCHEMBL8093075 | 0.86 | PPARA (0.48) | BCL2PTPN1RENATMKLK5 | |
| SCHEMBL8736231 | 0.86 | BCL2 (0.49) | BCL2PTPN1RENKLK5 | |
| SCHEMBL8945614 | 0.85 | REN (0.47) | BCL2PTPN1RENKLK5 | |
| SCHEMBL8945512 | 0.85 | REN (0.47) | BCL2PTPN1RENKLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773926-A1 | DIFLUOROSTATONE ANTIVIRAL AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996002499-A1 | DIFLUOROSTATONE ANTIVIRAL AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |