Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7422693 | 0.98 | GNAO1 (0.39) | PPARDGNAO1GNAI3GNAI1TSHR | |
| Hydrochloric Acid SCHEMBL29985358 | 0.92 | PPARD (0.39) | PPARDGNAO1GNAI3GNAI1TSHR | |
| SCHEMBL7453425 | 0.87 | PPARD (0.42) | PPARDGNAO1GNAI3GNAI1TSHR | |
| SCHEMBL17333598 | 0.84 | SIGMAR1 (0.47) | PPARDTSHR | |
| Trifluoroacetic Acid SCHEMBL29665655 | 0.79 | ITGB3 (0.34) | PPARDGNAO1GNAI3GNAI1ITGB3 | |
| SCHEMBL5552 | 0.76 | TSHR (0.41) | PPARDGNAO1GNAI3GNAI1TSHR | |
| SCHEMBL7268183 | 0.75 | PPARD (0.61) | PPARDTSHR | |
| SCHEMBL11514496 | 0.75 | PPARD (0.61) | PPARDTSHR | |
| SCHEMBL11323349 | 0.75 | PPARD (0.61) | PPARDTSHR | |
| Hydrochloric Acid SCHEMBL31019801 | 0.75 | TSHR (0.40) | PPARDGNAO1GNAI3GNAI1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815103-A1 | TRYPSIN AND THROMBIN INHIBITORS | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029327-A1 | TRYPSIN AND THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |