Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422318 | 1.00 | FFAR1 (0.51) | FFAR1LTB4RLTB4R2ALOX5PPARG | |
| SCHEMBL7378945 | 0.87 | MEN1 (0.48) | — | |
| SCHEMBL7423137 | 0.86 | FFAR1 (0.48) | FFAR1 | |
| SCHEMBL7426506 | 0.82 | MMP2 (0.45) | LTA4H | |
| SCHEMBL7421351 | 0.82 | MMP13 (0.48) | LTB4RLTB4R2 | |
| SCHEMBL7381782 | 0.81 | HPGD (0.47) | ALOX5 | |
| SCHEMBL7426589 | 0.81 | MAOB (0.51) | FFAR1LTB4RLTB4R2ALOX5 | |
| SCHEMBL7423336 | 0.81 | PARP10 (0.46) | FFAR1LTB4RLTB4R2ALOX5 | |
| SCHEMBL7421865 | 0.81 | MAOB (0.51) | FFAR1LTB4RLTB4R2ALOX5 | |
| SCHEMBL7424617 | 0.80 | MAOB (0.42) | FFAR1LTB4RLTB4R2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |