Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | TSPO | P30536 | 2/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834465 | 0.88 | LTB4R (0.45) | TSPOLTB4RLTB4R2ALOX5 | |
| SCHEMBL7424617 | 0.88 | MAOB (0.42) | LTB4RLTB4R2FFAR1CYP3A4FFAR4 | |
| SCHEMBL7421865 | 0.84 | MAOB (0.51) | LTB4RLTB4R2FFAR1ALOX5 | |
| SCHEMBL7426589 | 0.84 | MAOB (0.51) | LTB4RLTB4R2FFAR1ALOX5 | |
| SCHEMBL7421351 | 0.81 | MMP13 (0.48) | LTB4RLTB4R2 | |
| SCHEMBL7422318 | 0.81 | FFAR1 (0.51) | LTB4RLTB4R2FFAR1ALOX5 | |
| SCHEMBL7422822 | 0.81 | FFAR1 (0.51) | LTB4RLTB4R2FFAR1ALOX5 | |
| SCHEMBL7417897 | 0.79 | FOLH1 (0.45) | — | |
| SCHEMBL7423528 | 0.79 | LMNA (0.49) | — | |
| SCHEMBL7423137 | 0.79 | FFAR1 (0.48) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |