Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 16/20 | 0.67 |
| ▸ | MMP3 | P08254 | 16/20 | 0.67 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422973 | 1.00 | MMP2 (0.67) | MMP2MMP3SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL21895810 | 0.95 | MMP2 (0.61) | MMP2MMP3CA2MAPK1 | |
| SCHEMBL7367245 | 0.94 | MMP2 (0.60) | MMP2MMP3SLC1A2SLC1A1 | |
| SCHEMBL7382744 | 0.88 | MMP2 (0.55) | MMP2MMP3 | |
| SCHEMBL7362919 | 0.88 | MMP2 (0.55) | MMP2MMP3 | |
| SCHEMBL7382801 | 0.85 | MMP3 (0.58) | MMP2MMP3 | |
| SCHEMBL7382804 | 0.85 | MMP3 (0.58) | MMP2MMP3 | |
| SCHEMBL7365809 | 0.85 | MMP2 (0.53) | MMP2MMP3SLC1A2 | |
| SCHEMBL473644 | 0.85 | MMP2 (0.61) | MMP2MMP3CA2MAPK1 | |
| SCHEMBL27541801 | 0.85 | S1PR2 (0.55) | MMP2MMP3SLC1A2SLC1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1063991-A1 | STATIN-MATRIX METALLOPROTEINASE INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY LLC (US) | 2001-01-03 | — | — | EP | disclosed |
| WO-1999047138-A1 | STATIN-MATRIX METALLOPROTEINASE INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 1999-09-23 | — | — | WO | disclosed |