Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17791665 | 0.88 | LMNA (0.33) | LMNATP53ALDH1A1 | |
| SCHEMBL7960409 | 0.75 | ALDH1A1 (0.30) | LMNAALDH1A1 | |
| SCHEMBL42467 | 0.73 | TP53 (0.39) | TP53ALDH1A1 | |
| SCHEMBL19641937 | 0.73 | ALOX5 (0.39) | LMNA | |
| SCHEMBL150601 | 0.71 | TP53 (0.37) | TP53 | |
| SCHEMBL11412852 | 0.71 | TP53 (0.37) | TP53 | |
| SCHEMBL672963 | 0.71 | TP53 (0.37) | TP53 | |
| SCHEMBL638833 | 0.71 | TP53 (0.37) | TP53 | |
| SCHEMBL8386961 | 0.71 | TP53 (0.37) | TP53 | |
| SCHEMBL673528 | 0.71 | TP53 (0.37) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129243-B1 | NON-AQUEOUS ELECTROCHEMICAL CELL | HONEYWELL INC. (US) | 1988-10-19 | — | — | EP | claimed |
| WO-1996002494-A1 | BENZOCYCLOALKYLAMINE DERIVATIVES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-02-01 | — | — | WO | disclosed |
| US-4840947-A | Antiinflammatory and analgesic piperidin-4-yl-tetracyclic benzodiazepines and use thereas | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-06-20 | — | — | US | disclosed |
| EP-0265734-A1 | Piperidin-4-yl-tetracyclic benzodiazepines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-05-04 | — | — | EP | disclosed |