Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 5/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 8/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361335 | 0.95 | MMP3 (0.42) | ERAP2LNPEPMMP1MMP2MMP8 | |
| SCHEMBL7355861 | 0.92 | PSMB1 (0.41) | ERAP2LNPEPMMP1MMP3 | |
| SCHEMBL7364939 | 0.90 | ERAP2 (0.40) | ERAP2LNPEPMMP1MMP2MMP3 | |
| SCHEMBL7366734 | 0.90 | LNPEP (0.40) | ERAP2LNPEPMMP1MMP2MMP3 | |
| SCHEMBL7484700 | 0.90 | MMP3 (0.37) | ERAP2LNPEPMMP1MMP2MMP8 | |
| SCHEMBL7400006 | 0.90 | MMP3 (0.42) | ERAP2LNPEPMMP1MMP2MMP8 | |
| SCHEMBL7364809 | 0.88 | MMP3 (0.39) | MMP1MMP2MMP3CTSD | |
| SCHEMBL7357732 | 0.87 | MMP3 (0.46) | ERAP2LNPEPMMP1MMP2MMP3 | |
| SCHEMBL7357685 | 0.87 | MMP3 (0.44) | MMP1MMP2MMP8MMP9MMP3 | |
| SCHEMBL8903088 | 0.86 | MMP3 (0.37) | ERAP2LNPEPMMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025949-A1 | SUBSTITUTED 5-AMINO-1,3,4-THIADIAZOLE-2-THIONES | PROSCRIPT, INC. (US) | 1998-06-18 | — | — | WO | disclosed |